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API intermediates 2
Products Details
| Classfication | Product name | CAS NO. | Application |
| Anti-virus | |||
|
Baloxavir Marboxil 1985606-14-1 |
3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid | 119736-16-2 | Influenza virus infections |
| (R)-7-(benzyloxy)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4 c]pyrido[2,1-f][1,2,4]triazine-6,8-dione | 1985607-70-2 | ||
| 7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-ol | 1985607-83-7 | ||
| Favipiravir 259793-96-9 | 3,6-Dichloro-2-pyrazinecarbonitrile | 356783-16-9 | |
| 3,6-Difluoro-2-pyrazinecarbonitrile | 356783-28-3 | ||
| 3-Hydroxypyrazine-2-carboxamide | 55321-99-8 | ||
| 6-Bromo-3-hydroxypyrazine-2-carboxamide | 259793-88-9 | ||
| 6-Fluoro-3-oxo-3,4-dihydro-2-pyrazinecarbonitrile | 356783-31-8 | ||
| Remdesivir 1809249-37-3 | 2,3,5-Tri-O-benzyl-D-ribonolactone | 55094-52-5 | Anti Virus |
| 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate | 1911578-98-7 | ||
| 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine | 937046-98-5 | ||
| 7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine | 1770840-43-1 | ||
| N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester | 1354823-36-1 | ||
| (S)-2-ETHYLBUTYL 2-AMINOPROPANOATE HYDROCHLORIDE | 946511-97-3 | ||
| PYRROLO[1,2-F][1,2,4]TRIAZIN-4-AMINE | 159326-68-8 | ||
| Bictegravir 611493-60-7 | (1R,3S)-3-aminocyclopentanol (hydrochloride) | 1279032-31-3 | Anti-HIV |
| 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid | 1335210-23-5 | ||
| Dolutegravir 1051375-16-6 | 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid | 1335210-23-5 | |
| Anti-tumor | |||
| Afatinib 439081-18-2 | 7-Chloro-4-Hydroxy-6-Nitroquinazoline | 53449-14-2 | Non-small cell lung cancer |
| Trans-4-Dimethylaminocrotonic acid hydrochloride | 848133-35-7 | ||
| (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine | 314771-76-1 | ||
| Bortezomib 179324-69-7 | N-Pyrazinylcarbonyl-L-phenylalanine | 114457-94-2 | Multiple myeloma Mantle cell lymphoma |
| Isobutaneboronic acid | 84110-40-7 | ||
| 2-(1H-Benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate | 125700-67-6 | ||
| Carfilzomib 868540-17-4 | (2S)-2-amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone trifluoroacetate | 247068-85-5 | Multiple myeloma |
| Boc-L-leucine epoxyketone | 247068-82-2 | ||
| Dabigatran Etexilate Mesylate 872728-81-9 | 2-((4-Cyanophenyl)amino)acetic acid | 42288-26-6 | Thrombin inhibitors |
| Ethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2-yl-beta-alaninate | 212322-56-0 | ||
| Ethyl-N-[(2-{[(4-cyanophenyl)amino]methyl}-1-methyl-1H- benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alaninate | 211915-84-3 | ||
| Osimertinib 1421373-65-0 | 3-(2-chloropyrimidin-4-yl)-1-methylindole | 1032452-86-0 | Non-small cell lung cancer |
| N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl) pyrimidin-2 amine | 1421372-94-2 | ||
| Ceritinib 1032900-25-6 | 4-(5-isopropoxy-2-methyl-4-nitrophenyl)pyridine | 1032903-62-0 | |
| 5-methyl-2-(1-methylethoxy)-4- (4-piperidinyl)- benzenamine (dihydrochloride) | 1380575-45-0 | ||
| Capecitabine 154361-50-9 | 1,2,3-Triacetyl-5-deoxy-D-ribose | 62211-93-2 | Breast cancer Large intestine cancer |
| 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine | 161599-46-8 | ||
| Dasatinib 302962-49-8 | 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide | 302964-24-5 | Leukemia |
| N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide | 302964-08-5 | ||
| Decitabine 2353-33-5 | 3,5-O-bis(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride | 21740-23-8 | Acute/Chronic myeloid leukaemia Myelodysplastic syndromes |
| 1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose | 3601-90-9 | ||
| 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose | 3601-89-6 | ||
| Docetaxe | (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one | 132127-34-5 | Breast cancer Ovarian cancer |
| Lenvatinib 857890-39-2 | 4-Chloro-7-methoxyquinoline-6-carboxamide | 417721-36-9 | A multi-target tyrosine kinase inhibitor |
| 4-Amino-3-chlorophenol hydrochloride | 52671-64-4 | ||
| 4-Amino-3-chlorophenol | 17609-80-2 | ||
| 4-Amino-2-Methoxybenzoic Acid Methyl Ester | 27492-84-8 | ||
| Methyl 7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylate | 205448-65-3 | ||
| Methyl 4-chloro-7-Methoxyquinoline-6-carboxylate | 205448-66-4 | ||
| Palbociclib 571190-30-2 | 2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one | 1013916-37-4 | Breast cancer |
| 5-bromo-2-chloro-N-cyclopentylpyriMidin-4-aMine | 733039-20-8 | ||
| 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d] pyrimidin-7(8H)-one | 1016636-76-2 | ||
| 4-(6-aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester | 571188-59-5 | ||
| Ribociclib 1211441-98-3 | 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid | 1211443-58-1 | |
| 2-chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d] pyrimidine-6-carboxamide | 1211443-61-6 | ||
| Rucaparib 1859053-21-6 | Methyl 6-fluoro-1H-indole-4-carboxylate | 1082040-43-4 | Fallopian tube cancer Ovarian cance Peritoneal cancer |
| 8-Fluoro-1,3,4,5-tetrahydro-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one | 1408282-26-7 | ||
| Tipiracil HCl 183204-72-0 | 6-(chloromethyl) uracil | 18592-13-7 | Colorectal cancer |
| 2-amino-4,5-dihydro-3H-pyrrole (hydrochloride) | 7544-75-4 | ||
| Trifluridine 70-00-8 | 3,5-O-bis(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride | 21740-23-8 | |
| Cardio Cerebral Vascular | |||
|
LCZ696 Valsartan/Sacubitril (1:1) 936623-90-4 |
(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl) carbamate | 1426129-50-1 |
Heart Failure |
| (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl) amino)-2-methylpentanoic acid | 1012341-50-2 | ||
| (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methyl pentanoate (hydrochloride) | 149690-12-0 | ||
| Apixaban 503612-47-3 | 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester | 503614-91-3 | Venous Thromboembolism |
| 3-morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one | 545445-44-1 | ||
| Ethyl chloro[2-(4-methoxyphenyl)hydrazinylidene]acetate | 27143-07-3 | ||
| Edoxaban 912273-65-5 | Carbamic-acid,[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-,1,1-dimethylethyl ester 365998-36-3 | Thrombus | |
| Ethyl 2-(5-Methylpyridin-2-ylaMino)-2-oxoacetate | 1243308-37-3 | ||
| 4,5,6,7-tetrahydro-5-Methyl-Thiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride | 62002-31-7 | ||
| Ezetimibe 163222-33-1 | 4-[[(4-fluorophenyl)imino]methyl]- Phenol | 3382-63-6 | Hypolipidemic drugs |
| (4s)-3-[5-(4-fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone | 189028-93-1 | ||
| (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one | 189028-95-3 | ||
| Obeticholic Acid 459789-99-2 | (E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid | 1516887-33-4 | Hepatic Cirrhosis Fatty livers |
| (3α,5β)- Cholan-24-oic acid,6-ethylidene-3-hydroxy-7-oxo-,phenylmethyl ester | 1352328-66-5 | ||
| (E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid Methyl ester | 863239-59-2 | ||
| 3-Hydroxy-7-oxocholan-24-oic acid | 4651-67-6 | ||
| Olmesartan Medoxomi 144689-63-4 | 4-(1-Hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid ethyl ester | 144689-93-0 | Hypertension |
| 4-Cloromethyl-5-methyl-1,3-dioxol-2-one | 80841-78-7 | ||
| 4,5-Dimethyl-1,3-dioxol-2-one | 37830-90-3 | ||
| Triphenyl Methyl Olmesartan | 144690-92-6 | ||
| Rivaroxaban 366789-02-8 | 5-Chlorothiophene-2-carbonyl chloride | 42518-98-9 | Thrombus |
| 5-Chlorothiophene-2-carboxylicacid | 24065-33-6 | ||
| 4-(4-AMinophenyl)-3-Morpholinone | 438056-69-0 | ||
| 4-[4-[(5s)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholin-3-one hydrochloride | 898543-06-1 | ||
| Ticagrelor 274693-27-5 | (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride(1:1) | 1156491-10-9 |
Acute coronary syndromes |
| (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine（R）-2-hydroxy-2- phenylacetate | 376608-71-8 | ||
| 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol (2R,3R)-2,3-dihydroxybutanedioate | 376608-65-0 | ||
| 4,6-Dichloro-5-nitro-2-propylthiopyrimidine | 145783-14-8 | ||
| 4,6-dichloro-2-(propylthio)pyrimidin-5-amine | 145783-15-9 | ||
| Digestive system | |||
| Ilaprazole 172152-36-2 | 2-(chloromethyl)-4-methoxy-3-methyl-pyridine | 124473-12-7 | Proton pump inhibitors |
| 5-Amino-2-mercaptobenzimidazole | 2818-66-8 | ||
| 2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]thio]-6-(1H-pyrrol-1-yl)-1H-benzimidazole | 172152-35-1 | ||
| Vonoprazan fumarate (TAK-438 ) 1260141-27-2 | 4-(2-FLUOROPHENYL)-1H-PYRROLE-3-CARBONITRILE | 103418-03-7 | Inhibit gastric acid |
| 5-(2-fluorophenyl)- 1H-Pyrrole-3-carboxaldehyde | 881674-56-2 | ||
| 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)- 1H-Pyrrole-3-carboxaldehyde | 881677-11-8 | ||
| Immune System | |||
| Apremilast 608141-41-9 | N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl) acetamide | 6296-53-3 |
Plaque psoriasis Psoriatic arthritis |
| (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl) ethanamine | 608141-42-0 | ||
| (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl) ethylamine N-acetyl-L-leucine salt | 608141-43-1 | ||
| Bazedoxifene Acetate 1984841-33-3 | 1-(2-(4-(chloromethyl)phenoxy)ethyl)azepane (hydrochloride) | 223251-25-0 | Postmenopausal osteoporosis |
| 3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole | 198479-63-9 | ||
| 1-[4-(2-(Azepan-1-yl)ethoxy)benzyl]-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole | 198480-21-6 | ||
| Nervous System | |||
| lurasidone HCL 367514-88-3 | (R,R)-1,2-Cyclohexanedicarboxylic Acid | 46022-05-3 | Antipsychotic drug |
| (R,R)-1,2-bis(methanesulfonyloxymethyl)cyclohexane | 186204-35-3 | ||
| (1R,2R)-1,2-Cyclohexanedimethanol | 65376-05-8 | ||
| Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride | 2746-19-2 | ||
| Ramelteon 196597-26-9 | 1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one | 196597-78-1 |
Insomnia |
| Vilazodone 163521-12-8 | 3-(4-chlorobutyl)-1H-indole-5-carbonitrile | 143612-79-7 |
Major depressive disorder |
| 5-(1-piperazinyl)benzofuran-2-carboxylic acid ethyl ester | 163521-20-8 | ||
| 5-(1-piperazinyl)benzofuran-2-carboxamide | 183288-46-2 | ||
| Eletriptan 143322-58-1 | (R)-5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole | 143322-57-0 |
Menstrual migraine Migraine |
| 1-acetyl-3-[((2r)-1-methylpyrrolidin-2-yl)methyl]-5-[(e)-2-(phenylsulfonyl)vinyl]indole | 188113-71-5 | ||
| Rotigotine 92206-54-7 | 5-methoxyl-2-tetralone | 32940-15-1 |
Parkinson's disease Restless legs syndrome |
| (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride | 93601-86-6 | ||
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Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer’s risk. Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e) +A13 (1). |
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